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UV irradiation induces Snail expression by AP-1 dependent mechanism in human skin keratinocytes

✍ Scribed by Li, Yong; Liu, Ying; Xu, Yiru; Voorhees, John J.; Fisher, Gary J.


Book ID
119293645
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
464 KB
Volume
60
Category
Article
ISSN
0923-1811

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## Abstract Ultraviolet (UV) light‐induced activation of activator protein‐1 (AP‐1), resulting at least in part from oxidative stress, promotes skin carcinogenesis. It has not yet been determined whether elevating cellular phase II enzymes and glutathione (GSH) levels inhibits the AP‐1 activation.