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Silica Induces Plasminogen Activator Inhibitor-1 Expression through a MAPKs/AP-1-Dependent Mechanism in Human Lung Epithelial Cells

โœ Scribed by Hu, Y.B.; Lin, Z.; Feng, D.Y.; Li, X.; Chu, L.; Jiang, H.Y.; Peng, J.W.


Book ID
120543172
Publisher
Taylor and Francis Group
Year
2008
Tongue
English
Weight
794 KB
Volume
18
Category
Article
ISSN
1051-7235

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## Abstract Tumor cell expression of COXโ€2 has been implicated in the progression of murine and human lung cancer. Inhibition of COXโ€2 by nonsteroidal antiinflammatory drugs reduces the risk of cancer development in humans and suppresses tumor growth in animal models. However, the underlying mechan