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UV Induces GADD45 in a p53-Dependent and -Independent Manner in Human Keratinocytes

✍ Scribed by Tomoko Maeda; Adrian B. Sim; Duane A. Leedel; Prescillia P.S. Chua; Eugene G. Chomey; Le Luong; Victor A. Tron

Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
298 KB
Volume
7
Category
Article
ISSN
1203-4754

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## Abstract Aurora‐A is frequently altered in epithelial malignancies. Overexpressing Aurora‐A induces centrosome amplification and G2/M cell cycle progression. We have previously shown elevated level of Aurora‐A in ovarian cancer and activation of telomerase by Aurora‐A in human mammary and ovaria