UV-induced cross-linking of abscisic acid to binding proteins
β Scribed by Mathijs H.M. Cornelussen; Cees M. Karssen; Leendert C. van Loon
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 852 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0031-9422
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Levels of DNA strand breaks and DNA-protein cross-links (DPCs) were measured using the alkaline elution assay in normal human skin fibroblasts irradiated with 0-200 J m-2 of 254 nm UV radiation and incubated for 0-24 h. On incubation, the yields of both single-strand breaks (SSBs) and DPCs increased
Incubation of homogenates of rat nasal mucosa with acrolein resulted in the apparent formation of DNAprotein cross-links. However, inhalation exposure of male Fischer-344 rats to acrolein (2.0 ppm, 6 h) did not cause detectable DNA-protein cross-linking in the nasal respiratory mucosa. Simultaneous