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Utility of PCR amplification of T-cell receptor rearrangements in the definition of cutaneous T-cell lymphoma relapse

✍ Scribed by Duncan, Kary; Heald, Peter; Tallini, Giovanni; Crotty, Paul; Glusac, Earl


Book ID
121937820
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
185 KB
Volume
16
Category
Article
ISSN
0923-1811

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Clonal T-cell receptor ?-chain gene rear
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## Detection of clonal T-cell receptor (TCR )-chain gene rearrangement is a promising approach to distinguish between cutaneous T-cell lymphomas (CTCLs) and reactive T-cell infiltrates. Despite the improved sensitivity by using the polymerase chain reaction (PCR) rather than Southern blot analysis