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Cellular Coincidence of Clonal T Cell Receptor Rearrangements and Complex Clonal Chromosomal Aberrations-A Hallmark of Malignancy in Cutaneous T Cell Lymphoma

✍ Scribed by Marcus Muche, J.; Karenko, Leena; Gellrich, Sylke; Karhu, Ritva; Kytola, Soili; Kahkonen, Marketta; Lukowsky, Ansgar; Sterry, Wolfram; Ranki, Annamari


Book ID
110733084
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
247 KB
Volume
122
Category
Article
ISSN
0022-202X

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A clonal-specific polymerase chain reaction technique to detect T-cell receptor delta gene rearrangement in acute lymphoblastic leukaemia (ALL) and non-Hodgkin's lymphoma (NHL) was evaluated. It was applied to detect minimal residual disease. A sensitive and specific technique to detect minimal resi