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Utility of immunohistochemistry in bone marrow evaluation of T-lineage large granular lymphocyte leukemia

โœ Scribed by H.Lance Evans; Eric Burks; David Viswanatha; Richard S. Larson


Book ID
117818298
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
178 KB
Volume
31
Category
Article
ISSN
1532-8392

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The clinical significance of large cells
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## Abstract ## BACKGROUND Patients with chronic lymphocytic leukemia (CLL) that transforms to Richter syndrome (RS) frequently show atypical lymphocytes in bone marrow; however, a diagnosis of RS requires confirmation of the presence of sheets of large cells in bone marrow or lymph nodes. ## METH