Bone marrow aplasia associated with proliferation of large granular lymphocytes and subsequent transformation to acute lymphoblastic leukemia

T-γ large granular lymphocyte leukemia a

T-γ large granular lymphocyte leukemia associated with amegakaryocytic thrombocytopenic purpura, Sjögren's syndrome, and polyglandular autoimmune syndrome type II, with subsequent development of pure red cell aplasia

✍ David Ergas; Alexander Tsimanis; Mordechai Shtalrid; Chen Duskin; Alain Berrebi 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 68 KB 👁 1 views

## Abstract We present a female patient with T‐γ LGL leukemia, who was followed for the last 20 years. Over these years she developed several autoimmune disorders, including Sjögren's syndrome, Hashimoto's thyroiditis, premature ovarian failure (compatible with type II autoimmune polyglandular synd