𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Using SAR and QSAR analysis to model the activity and structure of the quinolone—DNA complex

✍ Scribed by Belsis Llorente; Fabrice Leclerc; Robert Cedergren

Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
974 KB
Volume
4
Category
Article
ISSN
0968-0896

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Structure and optical activity of the DN
Structure and optical activity of the DNA–aminoacridine complex
✍ Miss B. J. Gardner; S. F. Mason 📂 Article 📅 1967 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 912 KB

The electronic absorption and circular dichroism spectra of the DNA-acridine orange complex have been measured over a range of ionic strength, pH, and DNA phosphate to dye (P/D) ratios. Three circular dichroism bands associated with the long wavelength absorption band of acridine orange are induced

Probing the activation of protein C by t
Probing the activation of protein C by the thrombin-thrombomodulin complex using structural analysis, site-directed mutagenesis, and computer modeling
✍ Karin E. Knobe; Ann Berntsdotter; Lei Shen; John Morser; Björn Dahlbäck; Bruno O 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 647 KB

Protein C (PC) is activated to an essential anticoagulant enzyme (activated PC or APC) by thrombin (T) bound to thrombomodulin (TM), a membrane receptor present on the surface of endothelial cells. The understanding of this complex biological system is in part limited due to the lack of integration

A formal and structured approach to the
A formal and structured approach to the use of task analysis in accident modelling
✍ R.M. BOTTING; C.W. JOHNSON 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 406 KB

Recent work (Telford & Johnson, 1996;Johnson, 1997), involving the application of formal notations to analyse accident reports has shown that the quality of these accident reports is poor, so much so that their conclusions can be misleading. The proposed solution has been to use formal notations in