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Using mRNA expression profiling to determine anticancer drug efficacy

โœ Scribed by Gerrit Los; Fei Yang; Goli Samimi; Gerald Manorek; Ivelina M. Guerorguieva; Stephan Howell; Nielka van Erp; James K. Breaux


Book ID
102135448
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
263 KB
Volume
47
Category
Article
ISSN
0196-4763

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Concise prediction models of anticancer
โœ Tomotaka Tanaka; Keiji Tanimoto; Keiko Otani; Kenichi Satoh; Megu Ohtaki; Kazuhi ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 370 KB

## Abstract We developed concise, accurate prediction models of the __in vitro__ activity for 8 anticancer drugs (5โ€FU, CDDP, MMC, DOX, CPTโ€11, SNโ€38, TXL and TXT), along with individual clinical responses to 5โ€FU using expression data of 12 genes. We first performed cDNA microarray analysis and MT