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Vault-related resistance to anticancer drugs determined by the expression of the major vault protein LRP

✍ Scribed by Miguel A. Izquierdo; George L. Scheffer; Anouk B. Schroeijers; Mariska C. de Jong; Rik J. Scheper

Book ID
110257345
Publisher
Springer
Year
1998
Tongue
English
Weight
79 KB
Volume
27
Category
Article
ISSN
0920-9069

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Expression of the major vault protein LR
Expression of the major vault protein LRP in human non-small-cell lung cancer cells: Activation by short-term exposure to antineoplastic drugs
✍ Walter Berger; Leonilla Elbling; Michael Micksche πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 French βš– 419 KB πŸ‘ 2 views

Non-small-cell lung cancer (NSCLC) cells are characterised by resistance to the toxic impact of antineoplastic drugs both in vivo and in vitro. The lung resistance-related protein (LRP), identical with the human major vault protein, is over-expressed in a variety of tumour cells characterised by int