## Abstract ## Background To develop more efficient nonβviral vectors, we have previously described a novel approach to attach a nuclear localisation signal (NLS) to plasmid DNA, by generating a fusion protein between the tetracycline repressor protein TetR and an SV40 NLS peptide (TetRβNLS). The
β¦ LIBER β¦
Using magnetic forces to enhance non-viral gene transfer to airway epithelium in vivo
β Scribed by Xenariou, S; Griesenbach, U; Ferrari, S; Dean, P; Scheule, R K; Cheng, S H; Geddes, D M; Plank, C; Alton, E W F W
- Book ID
- 110039853
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 140 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0969-7128
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## Abstract ## Background Assistance with exit from endocytic vesicles is a key factor for nonβviral gene delivery, and is a particular challenge __in vivo__. We have evaluated the __in vivo__ use of chloroquine administered systemically, orally and/or locally for gene delivery to the liver. ## M