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Using Linkage Genome Scans to Improve Power of Association in Genome Scans

✍ Scribed by Kathryn Roeder; Silvi-Alin Bacanu; Larry Wasserman; B. Devlin

Book ID
117854740
Publisher
American Society of Human Genetics
Year
2006
Tongue
English
Weight
358 KB
Volume
78
Category
Article
ISSN
0002-9297

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Robust estimation of critical values for
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✍ Silviu-Alin Bacanu πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 106 KB

Estimation of study specific critical values for linkage scans (suggestive and significant thresholds) is important to identify promising regions. In this report, I propose a fast and concrete recipe for finding study specific critical values. Previously, critical values were derived theoretically o