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Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans

✍ Scribed by Yohan Bossé; François Bacot; Alexandre Montpetit; Johan Rung; Hui-Qi Qu; James C. Engert; Constantin Polychronakos; Thomas J. Hudson; Philippe Froguel; Robert Sladek; Martin Desrosiers

Book ID
106134806
Publisher
Springer
Year
2009
Tongue
English
Weight
904 KB
Volume
125
Category
Article
ISSN
0340-6717

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Genome scanning for complex disease gene
Genome scanning for complex disease genes using the transmission/disequilibrium test and haplotype-based haplotype relative risk
✍ Dr. Tara Cox Matise 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 294 KB

Two tests for allelic association were applied to a simulated complex disease for the Genetic Analysis Workshop 9. The transmission/disequilibrium test [Spielman et al., 19931 and the haplotype-based haplotype relative risk approach [Terwilliger and Ott, 19921 were used to detect disease-associated