Using label-free screening technology to improve efficiency in drug discovery
โ Scribed by Halai, Reena; Cooper, Matthew A
- Book ID
- 115513821
- Publisher
- Informa plc
- Year
- 2012
- Tongue
- English
- Weight
- 387 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1746-0441
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๐ SIMILAR VOLUMES
Drug discovery is a fast growing field and the number of compounds generated daily by the pharmaceutical industry is enormous. The necessity of developing new experimental strategies and analytical methods to rapidly screen the pharmacokinetics (PK) behavior of these compounds becomes a real challen
## Abstract We have previously reported the design and synthesis of ligands that stabilize Transthyretin protein (TTR) in order to obtain therapeutically active compounds for Familial Amyloid Polyneuropathy (FAP). We are hereby reporting a drug design strategy to optimize these ligands and map them