𝔖 Bobbio Scriptorium
✦   LIBER   ✦

High-throughput liquid chromatography/mass spectrometry method for the quantitation of small molecules using accurate mass technologies in supporting discovery drug screening

✍ Scribed by Ding, Xiao; Ghobarah, Hesham; Zhang, Xiaolin; Jaochico, Allan; Liu, Xingrong; Deshmukh, Gauri; Liederer, Bianca M.; Hop, Cornelis E. C. A.; Dean, Brian

Book ID
118275863
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
813 KB
Volume
27
Category
Article
ISSN
0951-4198

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

In vivo pharmacokinetic screening in cas
In vivo pharmacokinetic screening in cassette dosing experiments: the use of on-line prospekt® liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry technology in drug discovery
✍ Francis Beaudry; J. C. Yves Le Blanc; Michel Coutu; Nigel K. Brown 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 169 KB 👁 2 views

Drug discovery is a fast growing field and the number of compounds generated daily by the pharmaceutical industry is enormous. The necessity of developing new experimental strategies and analytical methods to rapidly screen the pharmacokinetics (PK) behavior of these compounds becomes a real challen

Demonstration of the capabilities of a p
Demonstration of the capabilities of a parallel high performance liquid chromatography tandem mass spectrometry system for use in the analysis of drug discovery plasma samples
✍ Walter A. Korfmacher; John Veals; Kimberly Dunn-Meynell; Xiping Zhang; Greg Tuck 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 102 KB 👁 3 views

There is a continuing need for increased throughput in the evaluation of new drug entities in terms of their pharmacokinetic (PK) parameters. This report describes an alternative procedure for increasing the throughput of plasma samples assayed in one overnight analysis: the use of parallel high per