Using genetics to probe host-virus interactions; the mouse mammary tumor virus model
β Scribed by Susan R Ross
- Book ID
- 108488889
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 463 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1286-4579
No coin nor oath required. For personal study only.
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Sequences (MRS) distantly related to mouse mammary tumor virus (MMTV) were found in genomes of a wide range of mammalian species using blot hybridization. The number of MRS copies and the degree of their homology with the hybridization probe varied and did not correlate with the taxonomic position o
## Abstract Antibody levels to mouse mammary tumor virus (MuMTV) in sera of C3H/BI, C57BL/6 and AKR mice were assayed by an enzymeβlinked immunosorbent assay (ELISA). It was found that antibody levels to MuMTV were highest in sera of C3H/Bi females which have a high incidence of breast cancer and l
Mammary cancer in mice is characterized by progression through defined stages of preneoplasia, with the most common preneoplastic stage being the hyperplastic alveolar nodule (HAN). We determined the relative levels of RNA expression of various cellular proto-oncogenes and endogenous mouse mammary t