Usefulness of proviral load measurement for monitoring of disease activity in individual patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis
✍ Scribed by Norihiro Takenouchi; Yoshihisa Yamano; Koichiro Usuku; Mitsuhiro Osame; Shuji Izumo
- Book ID
- 111739178
- Publisher
- Springer US
- Year
- 2003
- Tongue
- English
- Weight
- 286 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1355-0284
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## Abstract There is no effective therapy for human T‐cell lymphotropic virus type I (HTLV‐I)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP). Glucocorticoids are effective to reduce the motor disability in these patients, but its role as anti‐spastic drugs is unknown. Here it is repor
## Abstract A high human T‐cell lymphotropic virus type 1 (HTLV‐1) proviral load is described in HTLV‐1‐associated diseases, especially HAM/TSP. However, the cut‐off value to define high levels of HTLV‐1 proviral load is not well established. 281 HTLV‐1‐infected patients from the HTLV reference cen