## Abstract There is no effective therapy for human T‐cell lymphotropic virus type I (HTLV‐I)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP). Glucocorticoids are effective to reduce the motor disability in these patients, but its role as anti‐spastic drugs is unknown. Here it is repor
✦ LIBER ✦
Detection of human T-lymphotropic virus type I (HTLV-I) tax RNA in the central nervous system of HTLV-I–associated myelopathy/tropical spastic paraparesis patients by in situ hybridization
✍ Scribed by Dr. Tanya J. Lehky; Michael C. Levin; Nick Flerlage; Steven Jacobson; Cecil H. Fox; Scott Koenig; Shuji Izumo; Elichi Sato; Mitsuhiro Osame; Cedric S. Raine
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 985 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0364-5134
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## Abstract HTLV‐1 is the etiologic agent of ATL and HAM/TSP. The majority of HTLV‐1‐infected individuals remain asymptomatic, indicating that the infection alone is not sufficient to cause the diseases. It has been reported that cytokine gene polymorphisms, including polymorphisms at IL‐6 and IL‐1