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Usefulness of Genotypic Analysis of Resistance to Nucleoside Analogues in the Clinical Setting

✍ Scribed by M. Pérez-Olmeda; R. Rodríguez-Rosado; M. Gómez-Cano; C. Briones; V. Soriano

Publisher
Springer
Year
1999
Tongue
English
Weight
33 KB
Volume
18
Category
Article
ISSN
0934-9723

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✍ PLATT, GEORGINA M.; PRICE, CLIVE 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 396 KB

Treatment of Schizosaccharomyces pombe with the C5 DNA methyltransferase (C5Mtase) inhibitor 5-azacytidine (5-azaC) has previously been shown to induce G2 checkpoint-dependent cell cycle arrest. S. pombe strains defective in both the checkpoint control pathways and in DNA repair processes are sensit