Use of zinc borohydride in reductive amination: an efficient and mild method for N-methylation of amines
β Scribed by Bhattacharyya, Sukanta; Chatterjee, Arindam; Duttachowdhury, Shiti Kantha
- Book ID
- 120259537
- Publisher
- Royal Society of Chemistry
- Year
- 1994
- Weight
- 272 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1472-7781
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## Abstract A new and efficient method for the reductive methylation of amines is developed, which can be a good substitute for NaBH~3~CNβ or zincβmodified cyanoborohydrideβmediated reductive methylation reactions.
## Abstract A mild, environmentally friendly method for reduction of aromatic nitro group to amine is reported, using zinc powder in aqueous solutions of chelating ethers. The donor ether acts as a ligand and also serves as a co-solvent. Water is the proton source. This procedure is also a new meth