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Use of topical liposomes containing meglumine antimoniate (Glucantime) for the treatment of L. major lesion in BALB/c mice

✍ Scribed by Moosavian Kalat, S.A.; Khamesipour, A.; Bavarsad, N.; Fallah, M.; Khashayarmanesh, Z.; Feizi, E.; Neghabi, K.; Abbasi, A.; Jaafari, M.R.

Book ID: 122275939
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 541 KB
Volume: 143
Category: Article
ISSN: 0014-4894
DOI: 10.1016/j.exppara.2014.04.013

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Use of topical liposomes containing megl

Use of topical liposomes containing meglumine antimoniate (Glucantime) for the treatment of L. major lesion in BALB/c mice

✍ Moosavian Kalat, S.A.; Khamesipour, A.; Bavarsad, N.; Fallah, M.; Khashayarmanes 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 541 KB

## h i g h l i g h t s Topical liposomal Glucantime reduced lesion sizes in BALB/c model of leishmaniasis. The spleen parasite burden was significantly lower in the groups treated with TLG. Oleic acid in liposomal formulation did not increase the effect of the treatment. TLG could be a good candid