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Use of the immunotoxin N901-blocked ricin in patients with small-cell lung cancer

✍ Scribed by Carol Epstein; Tom Lynch; Jeremy Shefner; Patrick Wen; Deirdre Maxted; Virginia Braman; Pamela Ariniello; Felice Coral; Jerome Ritz

Publisher
John Wiley and Sons
Year
1994
Tongue
French
Weight
365 KB
Volume
57
Category
Article
ISSN
0020-7136

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✦ Synopsis

In patients with small-cell lung cancer (SCLC), relapse with resistant disease often causes deatlh. N90 I -blocked ricin (N90 I -bR), a murine monoclonal antibody (MAb)-blocked rich immunotoxin, is a potential therapeutic: for SCLC. N90 I -bR targets CD56, present on SCLC and cells of neuro-ectodermal origin.

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