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Use of single strand conformation polymorphism analysis to detect point mutations in human mitochondrial DNA

✍ Scribed by Anu Suomalainen; Emma Ciafaloni; Yasutoshi Koga; Leena Peltonen; Salvatore DiMauro; Eric A. Schon

Book ID: 118931420
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 581 KB
Volume: 111
Category: Article
ISSN: 0022-510X
DOI: 10.1016/0022-510x(92)90074-u

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## Summary Single‐stranded conformation polymorphism (SSCP) analysis was used to examine the mutations of the chloroplast 16S rRNA locus of streptomycin‐resistant mutants in __Nicotiana plumbaginifolia.__ DNA fragments of 121, 517, 968 and 1578 bp, each possessing a known point mutation, were gener