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Use of (S)-N-tert-butoxycarbonylaziridine-2-carboxylate derivatives for α-amino acid synthesis

✍ Scribed by Jack E. Baldwin; Christopher N. Farthing; Andrew T. Russell; Christopher J. Schofield; Alan C. Spivey


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
231 KB
Volume
37
Category
Article
ISSN
0040-4039

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Preparation and Use in Amino Acid Synthe
✍ Dieter Seebach; Matthias Hoffmann 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 612 KB

The title compound BDI is prepared on multigram scale, so clean that highly efficient in-situ double alkylations are feasible, in which the sequence of addition of the two either by resolution of the precursor 2-tert-butylimidazolidin-4-one (from glycine amide and pivalaldehyde) through different el