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(R)- and (S)-4-Alkoxy-2-tert-butyl-2,5-dihydroimidazole-1-carboxylates—New Chiral Glycine Derivatives for Amino Acid Synthesis

✍ Scribed by Dr. Stefan Blank; Prof. Dr. Dieter Seebach


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
251 KB
Volume
32
Category
Article
ISSN
0044-8249

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Separation of (R)- and (S)-tert-butyl 2-
✍ Matthias Hoffmann; Stefan Blank; Dieter Seebach; Ernst Küsters; Emil Schmid 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB 👁 1 views

The preparative separation of the enantiomers of the title compound, a versatile chiral building block for the synthesis of unnatural amino acid esters, by high performance liquid chromatography on a chiral stationary phase (CSP), is reported for the first time. The CSP consists of amylose-(3,5-dime