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Use of pyrocarbonates for chemical modification of histidine residues of horseradish peroxidase

✍ Scribed by Martine Urrutigoity; Michel Baboulene; Armand Lattes


Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
588 KB
Volume
19
Category
Article
ISSN
0045-2068

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A method for specific chemical modificat
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A method for the chemical modification of y-carboxyglutamic acid (Gla) residues in proteins is introduced that has the combined advantages of mildness, a high degree of specificity, and the ability to introduce a radiolabel at modification sites for ease in quantitation. Unlike other Gla modificatio