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An experiment on the chemical modification of essential histidine residues of lactate dehydrogenase

✍ Scribed by Ildefonso Díaz; Ignacio Nuñez de Castro; Miguel Angel Medina

Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
204 KB
Volume
21
Category
Article
ISSN
0307-4412

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The effects of a histidine (His) residue located on the C-terminal side of an asparaginyl (Asn) residue on the rate of deamidation were studied using Gly-Gln-Asn-X-His pentapeptides. The rates of deamidation of the pentapeptides were determined at 37 degrees C (I = 0.5) as function of pH, buffer spe