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Use of Polytomous Logistic Model in Matched Case-Control Studies

✍ Scribed by S. S. Ganguly; U. Naik Nimbalkar


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
367 KB
Volume
34
Category
Article
ISSN
0323-3847

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✦ Synopsis


Binary logistic model has been found useful for estimating odds ratio in case of dichotomous exposure variable under matched casecontrol retrospective design. We describe the use of polytomous logistic model for estimating odds ratios when the exposure of prime interest, relative to disease incidence, has more than two levels. An illustrative example is presented and discussed.


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## Abstract ## BACKGROUND: In case‐control studies on teratogenic risks of maternal drug use during pregnancy, the use of normal or malformed controls may lead to recall‐bias or selection bias. This can be avoided by using controls with a genetic disorder. However, researchers are hesitant to use