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Use of polyclonal antibodies against carcinogen–DNA adducts in analysis of carcinogenesis

✍ Scribed by Tomoyuki Shirai; Satoru Takahashi; Lin Cui; Yasuyuki Yamada; Mariko Tada; Fred F Kadlubar; Nobuyuki Ito


Book ID
119539719
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
228 KB
Volume
102-103
Category
Article
ISSN
0378-4274

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The use of rabbit polyclonal antibodies
✍ Bruna P. Brylawski; Marila Cordeiro-Stone; David G. Kaufman 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 599 KB

Polyclonal rabbit antibodies elicited against DNA with high levels of (+/-) 7r,8t-dihydroxy-9t,10t-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE-I) adducts were used to isolate DNA fragments modified by this carcinogen. DNA treated in vitro with different concentrations of BPDE-I was used as substra