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Monoclonal and Polyclonal Antibodies against Acetaldehyde-Containing Epitopes in Acetaldehyde-Protein Adducts

✍ Scribed by Yedy Israel, Esther Hurwitz, Onni Niemelä and Ruth Arnon


Book ID
123633277
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
978 KB
Volume
83
Category
Article
ISSN
0027-8424

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Antibodies against acetaldehyde-modified
✍ Onni Niemelä; Felix Klajner; Hector Orrego; Eva Vidins; Laurence Blendis; Yedy I 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 622 KB

Acetaldehyde, the primary metabolite of ethanol, binds covalently to proteins forming condensation products which have been recently shown to be immunogenic. To assess whether an antibody response against acetaldehyde-modified protein epitopes is associated with alcoholic liver disease, the serum im