Use of phased array coils for a determination of absolute metabolite concentrations
โ Scribed by Oliver Natt; Vitaliy Bezkorovaynyy; Thomas Michaelis; Jens Frahm
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 436 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
This work describes the use of phased array coils for a quantification of absolute metabolite concentrations. The method is demonstrated for singleโvoxel localized proton MRS of human brain with an eightโelement receiveโonly head coil. It is based on the transmitter reference amplitude of the body coil used for RF transmission. A relative sensitivity of every element of the phased array coil is derived from a combination of two reference scans without water suppression that correspond to either the body coil in transmitโreceive mode or the phased array coil in conjunction with body coil excitation. Experimental results were obtained at 2.9 T for both phantoms and 12 human subjects in different locations of gray and white matter. The data demonstrate that the procedure is technically robust and without a penalty in measuring time. Moreover, it takes full advantage of the signalโtoโnoise gain for quantitative proton MRS and may be extended to other phased array coils without the need for a recalibration. Magn Reson Med 53:3โ8, 2005. ยฉ 2004 WileyโLiss, Inc.
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