𝔖 Bobbio Scriptorium

✦ LIBER ✦

Use of pharmacokinetic/ pharmacodynamic modelling for starting dose selection in first-in-human trials of high-risk biologics

✍ Scribed by Balaji M. Agoram

Book ID: 108642196
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 634 KB
Volume: 67
Category: Article
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.2008.03297.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Development of good modelling practice f

Development of good modelling practice for physiologically based pharmacokinetic models for use in risk assessment: The first steps

✍ George Loizou; Martin Spendiff; Hugh A. Barton; Jos Bessems; Frédéric Y. Bois; M 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 196 KB

Evaluation of the pharmacokinetics–pharm

Evaluation of the pharmacokinetics–pharmacodynamics of fusidic acid against Staphylococcus aureus and Streptococcus pyogenes using in vitro infection models: implications for dose selection

✍ Olanrewaju O. Okusanya; Brian T. Tsuji; Jurgen B. Bülitta; Alan Forrest; Cathari 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 631 KB

Busulfan pharmacokinetics following intr

Busulfan pharmacokinetics following intravenous and oral dosing regimens in children receiving high-dose myeloablative chemotherapy for high-risk neuroblastoma as part of the HR-NBL-1/SIOPEN trial

✍ G.J. Veal; L. Nguyen; A. Paci; M. Riggi; M. Amiel; D. Valteau-Couanet; P. Brock; 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 608 KB

[ACS Symposium Series] Parameters for Pe

[ACS Symposium Series] Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment Volume 1099 || Extrapolating Dose in Vitro to Dose in Vivo of a Neurotoxic Pyrethroid Pesticide Using Empirical Approaches and a PBPK Model

✍ Knaak, James B.; Timchalk, Charles; Tornero-Velez, Rogelio 📂 Article 📅 2012 🏛 American Chemical Society ⚖ 691 KB

A 2 × 2 Factorial Design Rando

A 2 × 2 Factorial Design Randomised Control Trial Assessing the Efficacy of High Pressure Coronary Stent Deployment and Post-dilation to Achieve Relative Oversize Compared to Nominal Stent Deployment and Sizing in Patients at High Risk for Re-stenosis Using the Endeavor Drug-eluting Stent Versus Bare Metal Stents: The HEADROOM trial—Report of the First 100 Patients

✍ Joseph Matthews; Mark Pitney; Nigel Jepson; Robert Giles; Daniel Friedman; Roger 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 84 KB

news : US and UK offer attractive terms

news : US and UK offer attractive terms to lure high risk investment in deep water exploration : Ocean bottom cable survey navigation system on trial : New twist to data management and IT : Flexible vessel for seismic surveys : Winners of EAGE draw announced : BGS to remain public : Russian minerals on CD-ROM : News in brief : People in the News : Refinements to inherited modelling package : Integrated 2D and 3D seismic interpretation on PC : Geco-Prakla move to standardize TRIACQ recording system : Time-to-depth conversion highlighted in new release : Synchronized release from Landmark claimed as a first for integration

📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 211 KB