Use of organic modifiers to enhance chiral selectivity in capillary electrophoresis
✍ Scribed by T. J. Ward; M. Nichols; L. Sturdivant; C. C. King
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 517 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0939-4451
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## Enantioseparation of chiral thiobarbiturates using cyclodextrin-modified capillary electrophoresis The racemates of several chiral thiobarbiturates were separated by using different cyclodextrins in capillary electrophoresis (CE). Six neutral and negatively charged cyclodextrins 1 (CDs) were em
## Abstract The influence of seven differently methylated β‐cyclodextrin derivatives and of pure β‐cyclodextrin (β‐CD) on the enantiomeric resolution by capillary electrophoresis of six basic chiral pharmaceuticals is investigated. The methyl substitution pattern affects enantioselectivity much mor
## Abstract Chiral separation of tocainide, an antiarrythmic agent, was solved using the capillary electrophoresis method. Fifteen types of cyclodextrins were tried as chiral selective buffer additives, and baseline separation was achieved with five of them. The variables that were studied comprise