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Use of Multiplex Ligation-Dependent Probe Amplification (MLPA) in screening of subtelomeric regions in children with idiopathic mental retardation

✍ Scribed by Kausik Mandal; Vijay R. Boggula; Minal Borkar; Suraksha Agarwal; Shubha R. Phadke


Book ID
107598595
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
196 KB
Volume
76
Category
Article
ISSN
0019-5456

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Subtelomeric deletions detected in patie
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## Communicated by Ulf Landegren Subtelomeric rearrangements are responsible for 5% to 10% of cases of unexplained mental retardation. Despite their clinical relevance, methods to screen for these cytogenetically invisible abnormalities on a routine base are scarce. We screened patients with idiopa