## Communicated by Ulf Landegren Subtelomeric rearrangements are responsible for 5% to 10% of cases of unexplained mental retardation. Despite their clinical relevance, methods to screen for these cytogenetically invisible abnormalities on a routine base are scarce. We screened patients with idiopa
β¦ LIBER β¦
Investigation of patients with mental retardation and dysmorphic features using comparative genomic hybridization and subtelomeric multiplex ligation dependent probe amplication
β Scribed by Maria Kirchhoff; Tommy Gerdes; Stine Brunebjerg; Thue Bryndorf
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 70 KB
- Volume
- 139A
- Category
- Article
- ISSN
- 1552-4825
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## Abstract In a prospective study 94 individuals with mental retardation (MR) and dysmorphic features with normal conventional karyotypes were investigated by both subtelomeric FISH and high resolution CGH (HRβCGH) in order to compare the potential of the two techniques in this application. A tota
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