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Use of mixture models in determining laboratory criterion for identification of seropositive individuals: application to parvovirus B19 serology

✍ Scribed by R.A. Parker; D.D. Erdman; L.J. Anderson

Book ID: 119114926
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 646 KB
Volume: 27
Category: Article
ISSN: 0166-0934
DOI: 10.1016/0166-0934(90)90130-8

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A method for the analysis of age stratified antibody prevalence surveys is developed. The age specific distribution of the quantitative results of serological antibody tests is modelled as a mixture of seropositive and seronegative components. This yields maximum likelihood estimates of the prevalen