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Use of Gene Therapy in a Subcutaneous Murine Model of Lung Cancer

✍ Scribed by Manuel Rodrigo Garzón; Íñigo Tirapu Fernández de la Cuesta; Ainhoa Arina Iraeta; Miguel Noel Centelles Llorente; Javier Zulueta Francés

Book ID
119628747
Publisher
Elsevier Science
Year
2006
Tongue
Spanish
Weight
209 KB
Volume
42
Category
Article
ISSN
0300-2896

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## Abstract Activation of oncogenic __Kras__ in murine lung leads to the development of numerous small adenomas, only some of which progress over time to overt adenocarcinoma. Thus, although __Kras__ is the initiating oncogene, it is likely that secondary genetic events are required for progression