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Retroviral endostatin gene transfer inhibits growth of human lung cancer in a murine orthotopic xenotransplant model

โœ Scribed by Roland Kurdow; ArndS. Boehle; Maren Ruhnke; Renata Mendoza; Lars Boenicke; Bence Sipos; Bodo Schniewind; Peter Dohrmann; Holger Kalthoff

Publisher
Springer
Year
2003
Tongue
English
Weight
180 KB
Volume
388
Category
Article
ISSN
1435-2451

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## Abstract ## Background Efficient gene transfer to bone marrow derived mesenchymal stem cells (MSC) would provide an important opportunity to express potent anticancer agents in the tumour microenvironment because of their contribution to the tumour stroma. ## Methods HIVโ€based lentiviral vect