Use of flow cytometry to evaluate platelet function
β Scribed by E. Rossi; L Arrigoni; L Gallo; M Poggio; E Rizzi; U. Russo
- Book ID
- 119039072
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 86 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0049-3848
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## Abstract We performed a retrospective analysis of flow cytometry as a platelet crossmatching procedure. Sera from 17 alloimmunized refractory patients were tested against 32 donor platelets, which had been stored as plateletβrich plasma for up to 36 months. Overall, 14/32 (44%) crossmatches were
We have devised assays to detect both circulating alloantibodies to platelets (indirect assay) and platelet-association IgG and IgM (direct assay) using a flow cytometric technique. A variety of patients with immune thrombocytopenia were studied. Employment of a confocal lens in the flow cytometer i