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Use of DNAs Expressing HIV-1 Env and Noninfectious HIV-1 Particles to Raise Antibody Responses in Mice

✍ Scribed by Shan Lu; Joseph C. Santoro; Deborah H. Fuller; Joel R. Haynes; Harriet L. Robinson


Book ID
112270444
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
529 KB
Volume
209
Category
Article
ISSN
0042-6822

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The tat regulatory protein of HIV-1 was expressed as a fusion protein in E. coli and used as antigen to detect antibodies against HIV-tat (anti-tat) in the serum of HIV-1 infected children and adults. HIV-1-infected children showed a higher frequency (55%) of anti-tat than HIV-1-infected adults (36%