## Abstract A highly sensitive method has been developed for the determination of urinary 7โaminonitrazepam (7โANZP), the major metabolite of nitrazepam, using highโperformance electrospray liquid chromatography tandem mass spectrometry. The samples were prepared for analysis by adding 7โaminoclona
Use of direct-probe mass spectrometry as a toxicology confirmation method for demoxepam in urine following high-performance liquid chromatography
โ Scribed by Herbert Essien; S. Jason Lai; Steven R. Binder; David L. King
- Publisher
- Elsevier Science
- Year
- 1996
- Weight
- 528 KB
- Volume
- 683
- Category
- Article
- ISSN
- 0378-4347
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A method has been developed for the direct determination of paraquat and diquat in water samples. No sample preparation was required and analysis was done using high performance liquid chromatography coupled with ionspray tandem mass spectrometry. Heptafluorobutyric acid was used as the ion-pair age
Preparative high performance liquid chromatography (HPLC) coupled to tandem mass spectrometry has been used successfully for the isolation of several drug metabolites from urine. Nuclear magnetic resonance (NMR) spectroscopy has been employed to determine the exact chemical structure of these metabo