Renal impairment is common in patients after liver transplantation and is attributable in large part to the use of calcineurin inhibitor (CNI)-based immunosuppression. We sought to determine whether conversion to sirolimus-based immunosuppression was associated with improved renal function. In a sin
Use of daclizumab as initial immunosuppression in liver transplant recipients with impaired renal function
β Scribed by Sukru Emre; Gabriel Gondolesi; Kamil Polat; Menahem Ben-Haim; Tarik Artis; Thomas M. Fishbein; Patricia A. Sheiner; Leona Kim-Schluger; Myron E. Schwartz; Charles M. Miller
- Book ID
- 111722995
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 210 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1527-6465
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This work is a 1-yr interim analysis of a prospective, randomized, multicenter trial evaluating the effect of corticosteroid-free immunosuppression on hepatitis C virus-positive (HCV Ο© ) liver transplant recipients following liver transplantation (LT). Patients received tacrolimus and corticosteroid
Early renal dysfunction following liver transplantation is associated with increased morbidity and mortality. To evaluate the impact of delayed initiation of calcineurin inhibitor on renal function, we conducted a retrospective study comparing 118 liver transplant recipients who received rabbit anti
Sirolimus is used in patients with renal insufficiency after liver transplantation (LT) and especially in those with calcineurin inhibitor (CNI)-associated nephrotoxicity. We conducted a systematic review of all randomized controlled trials and observational studies to test the hypothesis that the u
Chronic renal dysfunction is a frequent and severe complication in solid-organ transplant recipients. Calcineurin inhibitors (CNIs) are the main pathogenic factors of renal dysfunction. Switching from CNIs to nonnephrotoxic drugs, such as mammalian target of rapamycin inhibitors (everolimus and siro