Use of cyclodextrins in the capillary electrophoretic separation of erythro- and threo-mefloquine enantiomers
โ Scribed by Salvatore Fanali; Emanuela Camera
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 425 KB
- Volume
- 745
- Category
- Article
- ISSN
- 1873-3778
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## Abstract The use of cyclodextrin derivatives for the efficient separation of enantiomeric drugs is described. Hydroxypropylation, methylation or carboxymethylation of the cyclodextrin not only result in a better solubility of the cyclodextrin in aqueous solutions, but also favor, __via__ additio
## Use of cyclodextrins in capillary electrophoresis: Resolution of tramadol enantiomers Capillary zone electrophoresis was successfully applied to the enantiomeric resolution of racemic tramadol. Both uncoated and polyacrylamide-coated capillaries were tested for method optimization using either