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Use of C5-Diamino-Substituted-Pyridine in Triple Helix Forming Oligonucleotides

✍ Scribed by Michel, J.; Moreau, S.

Book ID
127168690
Publisher
Taylor and Francis Group
Year
1999
Tongue
English
Weight
203 KB
Volume
18
Category
Article
ISSN
0732-8311

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The N-acetyl derivatives la and 2a of the aminotriazole and aminoimidazole 2'-deoxynucleosides 1 and 2 were synthesized as potential substitutes of protonated 2'-deoxycytidines within triple helix forming oligonucleotides for their recognition of DNA duplexes in a pH independent manner.