Use of area under the curve to estimate absolute bioavailability of digoxin
β Scribed by William G. Kramer; Richard H. Reuning
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 213 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Testing the equality of the area under a curve (AUC) for different dose groups is frequently done in pharmacokinetic research. Equality of AUCs is one indicator of bioequivalence. When the experimental unit must be sacrificed to obtain a response, AUC can be simply estimated using a linear combinati
A limited sampling model has been developed for Β―unarizine following a 30 mg oral dose in epileptic patients who were receiving phenytoin or carbamazepine or both, to estimate the area under the curve (AUC) and maximum plasma concentration (C max ). The model was developed using training data sets f