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USE OF ANTI-SINGLE-STRANDED DNA ANTIBODIES TO LOCALIZE AND QUANTIFY DENATURED DNA DURING CELL DEATH

โœ Scribed by C.E. Gagna; H.-R. Kuo; C. Hornan; I. Hammond; W.C. Lambert


Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
68 KB
Volume
24
Category
Article
ISSN
1065-6995

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We examined the possibility of using affinity columns coupled with anti-idiotype (Id) antibodies to selectively remove nephritogenic anti-DNA antibodies in order to determine their possible application to therapeutic plasmapheresis. Monoclonal anti-Id antibodies termed D1E2 or 1F5 were directed to i