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Use of Amino Composition to Predict Ligand-Binding Sites.

โœ Scribed by Shinji Soga; Hiroki Shirai; Masato Kobori; Noriaki Hirayama


Book ID
102008091
Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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## Abstract A new approach to predicting the ligandโ€binding sites of proteins was developed, using proteinโ€ligand docking computation. In this method, many compounds in a random library are docked onto the whole protein surface. We assumed that the true ligandโ€binding site would exhibit stronger af