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Use of a Titanium Thienyl Anion and a Simple Procedure for Introducing a Thiol Group into Thiophene in the Development of a Manufacturing Route to the 5-Lipoxygenase Inhibitor ZD4407

โœ Scribed by Hutton, Jonathan; Jones, Andrew D.; Lee, Stanley A.; Martin, David M. G.; Meyrick, Brian R.; Patel, Ian; Peardon, Rachel F.; Powell, Lyn

Book ID
127344120
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
141 KB
Volume
1
Category
Article
ISSN
1083-6160

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ChemInform Abstract: Use of a Titanium T
ChemInform Abstract: Use of a Titanium Thienyl Anion and a Simple Procedure for Introducing a Thiol Group into Thiophene in the Development of a Manufacturing Route to the 5-Lipoxygenase Inhibitor ZD4407.
โœ J. HUTTON; A. D. JONES; S. A. LEE; D. M. G. MARTIN; B. R. MEYRICK; I. PATEL; R. ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 1 views

Use of a Titanium Thienyl Anion and a Simple Procedure for Introducing a Thiol Group into Thiophene in the Development of a Manufacturing Route to the 5-Lipoxygenase Inhibitor ZD4407. -The synthesis of the title compound (IX) is achieved via a convenient method to the thiophene (III) by Ti-mediated