## Abstract GdโEthoxybenzylโDTPA (GdโEOBโDTPA) is a highly waterโsoluble paramagnetic contrast agent. Due to its protein binding of about 10% and its lipophilic residue, GdโEOBโDTPA exhibits both renal (30% of the dose) and hepatobiliary (70%) excretion in rats. Despite its lipohilic character, the
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Use of a neutral gadolinium chelate as a contrast medium for ERCP: case report
โ Scribed by Fauze Maluf-Filho; Manoel Souza Rocha; Paulo Sakai
- Book ID
- 118525338
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 116 KB
- Volume
- 61
- Category
- Article
- ISSN
- 1097-6779
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The introduction of a lipophilic moiety into the gadolinium chelate Gd-DTPA (dimeglumine gadopentetate, Magnevist) yielded Gd-EOB-DTPA (short form), which has potential as a magnetic resonance contrast agent for liver mass screening. The pharmacokinetics of Gd-EOB-DTPA in rats is nonlinear because a
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